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Bryonolic acid

CAS No. 24480-45-3

Bryonolic acid ( —— )

产品货号. M30903 CAS No. 24480-45-3

Bryonolic acid is a triterpenoid found in the Cucurbitaceae family of plants. Bryonolic acid has anti-inflammatory and antioxidant activities. It has been found to exhibit antineoplastic activity.

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥4040 有现货
50MG 获取报价 有现货
100MG 获取报价 有现货

生物学信息

  • 产品名称
    Bryonolic acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Bryonolic acid is a triterpenoid found in the Cucurbitaceae family of plants. Bryonolic acid has anti-inflammatory and antioxidant activities. It has been found to exhibit antineoplastic activity.
  • 产品描述
    Bryonolic acid is a triterpenoid found in the Cucurbitaceae family of plants. Bryonolic acid has anti-inflammatory and antioxidant activities. It has been found to exhibit antineoplastic activity.
  • 体外实验
    Bryonolic acid exerts anti-allergic activity by inhibiting homologous passive cutaneous anaphylaxis and delayed hypersensitivity. Bryonolic acid reduces nitric oxide by suppressing inducible nitric oxide synthase expression, indicating anti-inflammatory activity. In rat adrenal pheochromocytoma (PC12) cells, Bryonolic acid against N-methyl-D-aspartate (NMDA)-induced neurotoxicity, indicating it as a candidate neuroprotective agent for cerebral ischemic treatment.Bryonolic acid (1-200 μM) inhibits acyl-coA: cholesterol acyl transferase (ACAT) activity in rat liver microsomes in a concentration-dependent manner, blocking the biosynthesis of the cholesterol fatty acid ester tumour promoter. Bryonolic acid inhibits ACAT in intact cancer cells with an IC50 of 12.6 μM. Bryonolic acid inhibits both clonogenicity and invasiveness in MCF-7 MB-231, U87 and 3T3-EA cells.
  • 体内实验
    Bryonolic acid (500 mg/kg; i.p.; once) potently induces HO-1 in a manner dependent on the Nrf2-Keap1 pathway. Animal Model:Wild-type and Nrf2-/- mice Dosage:500 mg/kg.Administration:i.p.; once Result:Induced HO-1 in a manner dependent on the Nrf2-Keap1 pathway.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    ——
  • 研究领域
    ——
  • 适应症
    ——

化学信息

  • CAS Number
    24480-45-3
  • 分子量
    456.7
  • 分子式
    C30H48O3
  • 纯度
    >98% (HPLC)
  • 溶解度
    ——
  • SMILES
    ——
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

产品手册
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